Contribution of Excessive Sleep Duration to the Pathogenesis and Progression of Cardiovascular Disorders

Abstract

Cardiovascular disorders are a significant health concern worldwide, and understanding their complex pathogenesis and progression is crucial. Among lifestyle factors influencing cardiovascular health, sleep duration has garnered attention as a potentially modifiable determinant. While the detrimental impact of insufficient sleep has been extensively studied, the role of excessive sleep duration in cardiovascular diseases is gaining recognition. This paper aims to explore the extent to which prolonged sleep contributes to the development and advancement of cardiovascular disorders. Through a comprehensive review of observational and experimental studies, we investigate the association between excessive sleep duration and conditions such as hypertension, coronary artery disease, stroke, and heart failure. Potential mechanisms underlying this relationship are explored, including disruptions in circadian rhythm, alterations in inflammatory responses, glucose metabolism, and increased sympathetic activity. Although causality remains to be fully established, the findings suggest that maintaining an appropriate sleep duration could serve as a preventive strategy against cardiovascular diseases. The review also highlights the need for further research to elucidate the optimal sleep duration for cardiovascular health. Implementing interventions to correct sleep patterns and promote healthy sleep hygiene may offer potential benefits in mitigating cardiovascular risk.